Etifoxine is an #unregulated #anxiolytic and anticonvulsant #drug that was developed for #anxiety disorders in the 1960's. It is currently being investigated for peripheral nerve healing and #chemotherapy induced #pain.
Etifoxine has similar effects to #benzodiazepines with little to no withdrawal effects. It is mediated by GABAAα2 and binds directly β2 or β3 subunits of the GABAA. Etifoxine has a relative high oral bioavailability and a standard dose of 150mg per day for no more than 12 weeks.