AKA: Oxilofrine, hydroxyephrine, oxyephrine, and 4-HMP.
News: FDA has determined this is not a dietary ingredient after years of use.
This compound is #synephrine with a #methyl group attached to the alpha carbon.
#Methylsynephrine will have similar effects to synephrine. However, the half life will most likely be close to double that of synephrine. That is due to the #sterichinderance of the methyl group preventing #drug destruction via #mao or #monoamineoxidase.
#Oxilofrine activates beta adrenergic receptors. It is preferential to Beta 2 & 3, over beta 1. This is preferential for #performanceenhancingdrugs because beta-2 #adrenergic receptor will promote vasodilation in skeletal muscle and beta-3 will promote #fatloss.
Oxilofrine is a very mild central nervous system #stimulant due to the beta-hydroxyl group which prevents blood-brain-barrier permeability.